http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0113812-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0493 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0081 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
| filingDate | 1983-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1988-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0113812-B1 |
| titleOfInvention | Process for the preparation of 17-alpha-bromoethynyl and 17-alpha-iodoethynyl-17-beta-hydroxy steroids, and 17-alpha-bromoethynyl and 17-alpha-iodoethynyl-17-beta-hydroxy steroids |
| abstract | A process for preparing bromine- or iodine-unlabeled or radioactively labeled 17 alpha -bromoethynyl- and 17 alpha -iodoethynyl-17 beta -hydroxy steroids of the androstane and estrane series of the partial formula <IMAGE> wherein is a single bond or a double bond, V is a carbon-carbon bond or a methylene group, R is hydrogen or methyl, and X is bromine or iodine, from corresponding 17 alpha -ethynyl-17 beta -hydroxy steroids, comprises treating the starting steroid in an inert solvent with a brominating agent or an iodinating agent in the presence of a silver salt. The process enables production of old and new compounds having value as pharmacologically active compounds and also as diagnostic agents when the iodine or bromine is radioactive. |
| priorityDate | 1982-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.