| abstract |
Medicines useful for the treatment of anxiety states and pulmonary, renal, cardiovascular or circulatory disorders, containing, as active substance, a compound of formula: in which R 1 is 1-6 C alkvl, phenyl, 3-6 Cvcloalkvl C. phenylalkyl, cycloalkylalkyl or being H or alkyl, R 5 being alkenyl or alkinyl, the sum of the carbon atoms of R 3 , R 4 and R 5 being from 2 to 5, R 2 has the same meanings as R, and no longer the meaning in which n is 0, 1, 2 or 3, R 1 and R 2 can also form with the nitrogen atom to which they are attached a heterocyclic radical with 5, 6 or 7 members which can contain another heteroatom chosen from O and N and carry one or two substituents, Z is phenyl, pyridyl, thienyl, 2-thiazolyl or substituted phenyl, X and Y are H, halogen, 1-3 C alkyl, 1-3 C alkoxy, nitro or CF 3 , A represents N or CH, B represents N or CH. |