abstract |
The application relates to substituted 4'-hydroxy-α-ethylbenzhydroles for use as a medicament, in particular for the treatment of acute alcohol poisoning.n n n a) 4-Hydroxypropiophenon mit eine substituierte Phenylgruppe aufweisenden metallorganischen Verbindungen umgesetzt werden, oder b) substituierte 4'-Hydroxybenzophenonderivate mit eine Äthylgruppe aufweisenden metallorganischen Verbindungen umgesetzt werden, oder c) substituierte 4'-(Benzyloxy)-a-äthylbenzhydrole reduziert werden. The application further relates to a process for the preparation of these compounds, in which 4-hydroxypropiophenone with organometallic compounds having a substituted phenyl group a) 4-hydroxypropiophenone are reacted with organometallic compounds having a substituted phenyl group, or b) substituted 4'-hydroxybenzophenone derivatives are reacted with organometallic compounds having an ethyl group, or c) substituted 4 '- (Benzyloxy) -a-ethylbenzhydrole can be reduced. |