| abstract |
Benzo[f]quinoline derivatives which are useful as antihypertensive agents and are represented by the formula:n wherein R is hydrogen or lower alkyl, R 2 is hydrogen, lower alkyl, hydroxy-lower-alkyl or lower-alkoxy-lower-alkyl, R 3 and R 4 are the same or different and each is hydrogen, lower alkyl, halogen, lower alkoxy, benzyloxy or hydroxy, R 5 and R 6 are the same or different and each is hydrogen, straight or branched alkyl, aralkyl or cycloalkyl, or R 5 and R 6 together with the adjacent nitrogen atom form a heterocycle, and the dotted line in the ring is an optional bond between 1- and 2-positions, and pharmaceutically acceptable acid addition salts thereof. |