| abstract |
The invention relates to an absorbable pharmaceutical preparation for enteral administration, characterized in that it contains a therapeutically effective amount of an essentially orally inactive β-lactam antibiotic in an absorption-increasing amount of a potentiator which consists of an aliphatic C 2 -C 18 fatty acid, a mono-, di- or triglyceride of a C 2 -C 12 fatty acid, a partial ester or full ester of propylene glycol, polyethylene glycol or a carbohydrate with a C 2 -C 12 fatty acid, a pharmaceutically acceptable ester or ether thereof or a mixture of the potentiators mentioned; if desired in conjunction with a pharmaceutically acceptable carrier. The invention also relates to the manufacture of such preparations. The preparations can be used to combat or prevent infectious diseases. |