| abstract |
1,4-Dihydropyridine derivatives of the formula:and their pharmaceutically acceptable acid addition salts; whereR is aryl or heteroaryl;R<sup>1</sup> and R<sup>2</sup> are each independently C<sub>1</sub>-C<sub>4</sub> alkyl or 2-methoxyethyl; Y is -(CH<sub>2</sub>)<sub>2</sub>-, -(CH<sub>2</sub>)<sub>3</sub>-, -CH<sub>2</sub>CH(CH<sub>3</sub>)-or-CH<sub>2</sub>C(CH<sub>3</sub>)<sub>2</sub>-;R<sup>3</sup> isThe compounds have utility as anti-ischaemic and antihypertensive agents. |