http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0104566-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1983-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1987-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0104566-B1 |
| titleOfInvention | Process for the preparation of 5,11-dihydro-11-((4-methyl-1-piperazinyl)-acetyl)-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one |
| abstract | 1. Process for preparing 5,11-dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H- -pyrido[2,3-b][1,4]-benzodiazepin-6-one or the salts thereof with inorganic or organic acids, characterised in that 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one of formula I see diagramm : EP0104566,P8,F1 is reacted in a solvent conventionally used for lithiation reactions first with at least two equivalents of a lithium alkyl or lithium aryl at temperatures of between -60 and 0 degrees C and subsequently with a (4-methyl-1-piperazinyl)-acetate of general formula III see diagramm : EP0104566,P8,F2 wherein R represents an alkyl group with 1 to 10 carbon atoms, a phenyl or phenylalkyl group with 1 to 3 carbon atoms in the alkyl part, and the compound thus obtained is isolated and, if desired, converted into the salts thereof with inorganic or organic acids. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7123562-B2 |
| priorityDate | 1982-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.