| abstract |
A process for preparing a 5-perfluoroalkyldihydrouracil derivative of the general formulawherein R<sub>f</sub> represents a perfluoroalkyl group, each of R<sup>1</sup> and R<sup>2</sup> represents a hydrogen atom, or an alkyl, cyloalkyl, aryl, aralkyl or heterocyclic group, and Y is an oxygen or sulfur atom, which comprises (a) reacting a compound of the general formulawherein X represents a halogen atom or a hydroxyl group, with a urea derivative of the general formulaprovided that when X is a hydroxyl group and at least one of R<sup>1</sup> and R<sup>2</sup> is a hydrogen atom, said reaction is carried out in the presence of a consensing agent, or (b) cyclizing a compound of the general formulaand a novel intermediate compound of the above formula (IV). |