http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0101641-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 |
| filingDate | 1983-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca5806def32463c08710de846fc7dff8 |
| publicationDate | 1984-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0101641-A2 |
| titleOfInvention | Sulfonylamino-aza-bicyclo-alkyl derivatives |
| abstract | A compound of formula (1), or pharmaceutically acceptable salt, or N-oxide thereof, or a solvate of any of the foregoing:n wherein: one of X and Y is CO and the other is NR 9 , R 9 being hydrogen or as defined with R 1 ; A is a groupn n orn wheren p and q each independently are 0 to 2; Z is O or S; nis 0 or 1; and one of R 6 and R 7 when n=0 is C 1-4 alkoxy, C 1-4 alkoxycarbonyl, hydroxy of C 1-4 alkyl optionally substituted by hydroxy, C 1-4 alkoxy or C 1-4 acyloxy, and the other is hydrogen or C 1-4 alkyl or one of R 6 , R 7 and R 8 when n=1 is C 1-4 alkyl and the other two are the same or different and are hydrogen or C 1-4 alkyl. n R 5 is C 1-7 alkyl, -(CH 2 ) s R 10 , s being 0 to and R 10 being C 3-8 cycloalkyl, -(CH 2 ) t R 11 , t being 1 or 2 and R 1 being thienyl or phenyl optionally substituted by one or two substituents selected from C 1-4 alkoxy, trifluoromethyl, halogen, nitro, carboxy, esterified carboxy and C 1-4 alkyl optionally substituted by hydroxy, C 1-4 alkoxy, carboxy, esterified carboxy or in vivo hydrolysable acyloxy:n and either R 1 is C 1-6 alkoxy, C 1-6 alkylthio or, together with R 9 when Y is NR 9 , C 1-2 alkylene, one of R 2 , R 3 and R 4 is R 15 SO 2 NR 20 where R 15 is C 1-6 alkyl, or amino optionally substituted by one ortwo groups selected from C 1-6 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl C 1-4 alkyl, phenyl or phenyl C 1-4 alkyl groups, any of which phenyl groups may be substituted by one or more groups selected from halogen, trifluoromethyl, C 1-6 alkyl, C 1-6 alkoxy and nitro, or optionally substituted by C 4 - 5 polymethylene and R 20 is hydrogen or C 1-4 alkyl, and the other two of R 2 , R 3 and R 4 together are C 1-2 alkylenedioxy, or the other two are the same or different and are selected from hydrogen, halogen, trifluoromethyl, C 1-6 alkyl, C 1-6 alkoxy, C 1-7 acyl, carboxylic C 1-7 acylamino, C 1-6 alkylsulphonyl, C 1-6 alkylsulphinyl, hydroxy, nitro or amino, aminocarbonyl or aminosulphonyl optionally N-substituted by one or two C 1-6 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl C 1-4 alkyl groups or optionally N-disubstituted by C 4 - 5 polymethylene, or R 1 and R 2 together are C 1-2 alkylendioxy; one of R 3 and R 4 is R 15 SO 2 NR 20 as defined, and the other is selcted from the groups defined hereinbefore for R 3 and R 4 . |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093265-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8012956-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0189002-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0189002-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5256656-A |
| priorityDate | 1982-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.