| abstract |
Compounds of formula (I)and acid addition salts thereof, wherein R<sup>1</sup> is hydrogen, hydroxy, alkoxy, aryloxy, aralkoxy, heteroaryloxy or heteroaralkoxy; and one of R<sup>2</sup>, R<sup>3</sup> and R<sup>4</sup> is hydrogen and the others are the same or different and each is hydrogen, alkyl, aryl, aralkyl, heteroaryl or heteroaralkyl; or R<sup>2</sup> is hydrogen andis mono- or bi-cyclic amino, inhibit enterotoxin-induced secretion into the small intestine and are, therefore, useful in treating enterotoxin induced diarrhoea in humans and scours in animals. |