http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0096816-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1983-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c669d88fc3c869ad054420d7d01162b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6911913a3c7319ae8167cdf9e2732c5 |
| publicationDate | 1983-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0096816-A2 |
| titleOfInvention | New 5-(pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole derivatives as anti-inflammatory and analgesic agents |
| abstract | Substituted 5-(pyrrol-2-oyl)-1,2-dihydro-pyrrolo [1,2-a]-pyrrole derivatives are disclosed having the structural formula:or a pharmaceutically acceptable salt, ester or amide thereof whereinR is, e.g., hydrogen or loweralkyl;R' is hydrogen, loweralkyl or lower haloalkyl;R<sup>2</sup>Z can be at any available positions and R<sup>2</sup> is R;n is 1 to 3;R<sup>3</sup> is, e.g., hydroxy or loweralkoxy;Y is, e.g., oxygen, sulfur or H with the proviso that when Y is H, R is not present;Z is, e.g.,-0-,-S-or halo providing that when Z is halo, R is not present. These compounds have been prepared via decarboxylation of the corresponding 1,7-dicarboxylate prepared from condensation of a dialkyl 1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-7-dicarboxylate 7 carboxylic acid with an appropriately substituted 2-pyrroyl chloride, or conversely, an acid chloride of the former bicyclic compound with a substituted pyrrole. The compounds are analgesic and antiinflammatory agents of high activities but low ulcerogenic side effects. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4895956-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0307034-A1 |
| priorityDate | 1982-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 406.