abstract |
Composite plasmids which comprise (A) a drive-unit region derived from a plasmid (a) capable of propagating in a Coryneform glutamic acid-producing bacterium, and (B) a gene fragment derived from a plasmid (b) capable of propagating in Escherichia coli or Bacillus subtilis and having at least a region expressing drug registance, are disclosed. The plasmids can be incorporated into Coryneform glutamic-acid producing bacteria. |