| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0d3f7fccce51b1900e29dfe34cf59b2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate |
1983-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d029cdfdd3f61bf30acb97aa12dbdc2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b802ac27b29b08b551c2b5beab42da3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d997443c7cb3bb01306f6b8eb933f337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a56f94c52cab71689840658953b200ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06421c1cf8b7226f1ea2772c3da81ecd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3163741e9fa010db9bbd6b3aa71f4795 |
| publicationDate |
1983-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0092193-A2 |
| titleOfInvention |
Process for isolating tetracyclines |
| abstract |
The subject of this invention is a method for isolating tetracyclines from the broth after the biosynthesis or from the mother liquor after isolating crude bases by means of ion-exchange and sorption resins. n The broth or the acid mother liquor are passed through a bed of slightly alkaline anion-exchange resin with the functional groups blocked by a mineral acid anion. The antibiotic containing eluate is adsorbed on the bed of macroporous resin and then desorbed by washing with a 15-60% aqueous acidified solution af acetone or of methanol. The pure compound is isolated from the eluate by a well-known method. The beds of anion-exchange and sorption resins are regenerated with an aqueous solution of acetone or of methanol containing to 80% by volume of the organic solvent with addition of 0,4-6% by weight of sodium or potassium hydroxide or of ammonia. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107935879-A |
| priorityDate |
1982-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |