| abstract |
Compounds of the formula:-wherein A stands for -(CH<sub>2</sub>)<sub>2</sub>-, which may optionally bear one or two methyl substituents, or for -(CH<sub>2</sub>)<sub>3</sub>-, R' stands for a defined (3-4C)alkyl radical, a cyclopropyl radical, or a phenyl radical which may optionally bear a defined substituent, and R<sup>2</sup> and R<sup>3</sup>, which may be the same or different, stand for a methyl or ethyl radical, and pharmaceutically-acceptable acid-addition salts thereof. Process for the manufacture of said compounds. Pharmaceutical compositions comprising one of said compounds and a pharmaceutical diluent or carrier. The compounds are 5-hydroxytryptamine antagonists. |