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filingDate 1983-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1985-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1985-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0089693-B1
titleOfInvention Steroid esters of n-(2-halogen-ethyl)-n-nitroso-carbamoyl amino acids and their peptides, and process for their preparation
abstract PCT No. PCT/EP83/00090 Sec. 371 Date Nov. 17, 1983 Sec. 102(e) Date Nov. 17, 1983 PCT Filed Mar. 23, 1983 PCT Pub. No. WO83/03414 PCT Pub. Date Oct. 13, 1983.Steroid-N-(2-halogen ethyl)-N-nitroso-carbamoyl-amino acid or peptide esters of the general formula: <IMAGE> +TR <IMAGE> where R1 and R2, which may be identical or different, mean the radical of an amino acid beyond the C atom in the beta position (if present), R3 means the radical of a steroid or a stilbene derivative pharmacologically similar in action, n is a number from 0-5 and Hal stands for chlorine or fluorine, as well as the method for preparing them by the conversion of an appropriate carbamoyl-amino acid or carbamoyl-peptide in a manner known per se with steroid alcohols or the conversion of steroid-amino acid or steroid-peptide esters with corresponding N-nitroso-carbamoylation or corresponding N-nitroso-carbamoyl-amino acids or peptides in a manner known per se.
priorityDate 1982-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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