| abstract |
Substituted octahydro-1H-indole-2-carboxylic acids having the formulan wherein R. is hydrogen or lower alkyl; R 6 is hydrogen, lower alkyl or benzyl; R, is hydrogen or lower alkyl; Ar is phenyl or phenyl substituted with 1 or 2 substituents selected from the group consisting of fluorine, chlorine, bromine, lower alkyl, lower alkoxy, hydroxy or amino; and m is 0 to 3; wherein lower alkyl and lower alkoxy contain 1 to 4 straight or branched carbon atoms; and the pharmaceutically acceptable salts thereof, are disclosed. The compounds and the salts are useful for treating hypertension. |