http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0088117-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8445046b074c98d4f34b82bd552bfa2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate | 1982-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8222435fdf6ca010896bf9e1dec86aa7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31a4cff6280b971507c833497046f2dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f88c5ee25f2a95393b5a88a1501880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b157ecfca6e248873e05d05d0d0c448 |
| publicationDate | 1983-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0088117-A1 |
| titleOfInvention | METHOD FOR PRODUCING HUMAN INSULIN OR B-30 ESTERS THEREOF. |
| abstract | Human insulin or its B-30 esthers are prepared by reaction of an insulin derivative corresponding to the formula $ (6,) $ where R is a hydroxyl or amino acid radical different from threonine, and -A- and -B- represent the chains A- and B- with the same amino acid sequence as in human insulin, with an L-threonine derivative protected by a carboxyl and optionally protected by a hydroxyl in a variable concentration between two and approximately six moles per liter in the presence of trypsin or of an enzyme analogous to trypsin in a reaction medium containing water and optionally also an organic co-solvent at a pH value between 5 and 9 and at a temperature below 50oC, this reaction being optionally followed by the extraction of all the protective groups present. |
| priorityDate | 1982-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.