| abstract |
5-fluoro-2'-deoxyuridine derivatives expressed by general formula (1) and their pharmacologically permissible saltsn wherein A indicates a saturated or unsaturated divalent aliphatic hydrocarbon group having 1 to 30 carbon atoms; the letter n indicates 0 or 1, and when n is 0, it indicates that Y is directly bound to an oxygen atom; Y represents a hydrogen atom, phenyl group, or substituted phenyl group; however, when Y is a hydrogen atom, n is 1; R indicates a hydrogen atom or alcohol-protecting group. n These compounds have a very strong antitumor activity. |