| abstract |
New active pharmaceutical ingredients with valuable analgesic properties are described, which can be used as medicines in the form of pharmaceutical preparations. These are morphine derivatives of the formula <IMAGE> wherein R¹ is hydrogen, lower alkyl, lower alkenyl, lower cycloalkyl-lower alkyl, cyano-lower alkyl, aryl-lower alkyl or heteroaryl-lower alkyl, R² (C2-7) alkanoyl , Arylcarbonyl, trifluoromethylcarbonyl or the group RR'C (OH) -, R (C1-6) alkyl and R 'are hydrogen or lower alkyl, and their pharmaceutically acceptable acid addition salts. |