| abstract |
Compound of formula in which the carboxy group at C 3 is endo-oriented to the bicyclic cis-configured ring system and in which R 1 is hydrogen, allyl, vinyl or a side chain of an optionally protected naturally occurring a-amino acid, R 2 = hydrogen, alkyl, alkenyl or aralkyl, Y = Hydrogen or hydroxy. Z = hydrogen or Y and Z = together oxygen and X = alkyl, alkenyl, cycloalkyl, optionally by alkyl, alkoxy. Hydroxy, halogen, nitro. Amino, alkylamino, di-alkylamino or methylenedioxy mean mono-, di- or trisubstituted aryl or indol-3-yl, processes for their preparation, agents containing them and their use. |