abstract |
Process for producing a storage-stable, crosslinked hemoglobin preparation with a high oxygen transport capacity, and the hemoglobin preparation produced by this process.n n n Such hemoglobin preparations can be prepared by reducing a hemoglobin solution with an oxygen-consuming reducing agent to pO 2 = 0 mbar and then adding an effector, crosslinking with a dialdehyde, reducing with a carbonyl group-specific reducing agent, ultrafiltration in the circuit and adding a reducing agent to the product stabilized. |