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filingDate 1982-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1983-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0078961-A2
titleOfInvention Process for manufacturing a stable cross-linked preparation of haemoglobin having a high oxygen transportation capacity, and preparation of haemoglobin so obtained
abstract Process for producing a storage-stable, crosslinked hemoglobin preparation with a high oxygen transport capacity, and the hemoglobin preparation produced by this process.n n n Such hemoglobin preparations can be prepared by reducing a hemoglobin solution with an oxygen-consuming reducing agent to pO 2 = 0 mbar and then adding an effector, crosslinking with a dialdehyde, reducing with a carbonyl group-specific reducing agent, ultrafiltration in the circuit and adding a reducing agent to the product stabilized.
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