| abstract |
The use of novel imidazolecarboxylic acid derivatives of the following general structure which are useful as antihypertensives, cardiotonics and antithromboticsn wherein Q and T are an oxygen or sulfur atom; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; R 1 is hydrogen or -CH(R 3 )R 4 ; R 2 is lower alkoxy, phenoxy or phenoxy substituted at the ortho, meta, or para position with lower alkyl, lower alkoxy, hydroxy, halogen, trifluoromethyl, lower alkylthio, lower alkylsulfone, or lower alkylsulfoxide; R 3 is hydrogen or lower alkyl; R 4 is hydrogen, hydroxy, lower alkoxy, lower alkylcarbonyl, -ON0 2 or halogen; and their pharmaceutically acceptable salts thereof. |