abstract |
A compound of formula (I), and salts thereof:n wherein:n R, is a C 1-6 alkoxy group; R 2 and R 3 are the same or different and are hydrogen, halogen, CF 3 , C 1-7 acyl, amino, C 1-7 acyl amino, aminocarbonyl or aminosulphone optionally substituted by one or two C 1-6 alkyl groups; C 1-6 alkyl-SOn wherein n is 1 or 2; or nitro; R 4 is hydrogen or C 1-6 alkyl; R 5 is C 1-6 alkyl or a group -(CH 2 ) s R 6 wherein s is 1 or 2 and R 6 is C 3-8 cycloalkyl or phenyl, which phenyl may optionally be substituted by one or two substituents selected from C 1-6 alkyl, C 1-4 alkoxy, CF 3 and halogen; n is 0 to 3; p is 3 to 6; and r plus s is 2 to 5; may be used for the treatment of disorders of the gastro-intestinal function. |