abstract |
Dimedon is made from 3,3-dimethyl-5-oxo-hexanoic acid, which in turn can be produced from isophorone via its ozone addition product and subsequent hydrolysis, by dehydrating it to give the corresponding 4,4,6-trimethyl-3,4-dihydro-1 , 2-pyrone and obtained by treating the latter with an alkali alcoholate. |