| abstract |
Halohydrins of the formula:n wherein R and R 1 , which may be the same or different, are hydrogen or alkyl; X, Y and Z are each independently hydrogen, fluorine or chlorine and A is chlorine or bromine, are prepared by reacting a tertiary alcohol of the formulan or a substituted alkene of the formulan with chlorine, bromine, hypochlorous acid or hypobromous acid in an aqueous medium. Preferably the aqueous medium is a mixture of water and an amide solvent selected from dimethyl formamide, diethyl formamide and dimethyl acetamide and the reaction is carried out in the presence of hydrogen peroxide. n The halohydrins are useful intermediates for fungicides. |