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filingDate 1981-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1985-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1985-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0062068-B1
titleOfInvention N-phthalidyl-5-fluorouracil derivatives
abstract PCT No. PCT/JP81/00260 Sec. 371 Date May 21, 1982 Sec. 102(e) Date May 21, 1982 PCT Filed Sep. 30, 1981 PCT Pub. No. WO82/01370 PCT Pub. Date Apr. 29, 1982.The present invention relates to novel N-phthalidyl-5-fluorouracil derivatives represented by the general formula <IMAGE> wherein one of R1 and R2 represents phthalidyl group <IMAGE> (wherein R3 is a hydrogen atom, a halogen atom or a group selected from alkoxyl groups or alkyl groups) and the other represents a hydrogen atom, an acyl group or a cyclic ether group; <IMAGE> (wherein n is 1 or 2) or R1 and R2 represent the same phthalidyl group; <IMAGE> (wherein R3 has the same meaning as that defined above) and provides a compound which has antitumor activity and less toxicity and can be used as a cancerocidal agent.
priorityDate 1980-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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