http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0061688-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00 |
filingDate | 1982-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1985-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1985-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0061688-B1 |
titleOfInvention | Process for the controlled microbial degradation of bile acids |
abstract | 1. A process for the microbiological degradation of bile acids by aerobic culture of microorganisms in an aqueous medium using a starting material containing bile acids as carbon source for the growth of the microorganisms, characterized in that, for selective degradation of the steroid-C17-carboxyalkyl side chain to the alpha -propionic acid residue and for simultaneous conversion of the steroid-A ring into the 3-oxo-4-ene and/or the 3-oxo-1,4-diene structure, defective microorganism mutants are used which are capable of growth on vegetable or animal sterol compounds containing a C17-alkyl or alkenyl side chain as sole carbon source and which form 3-oxopregna-4-ene-20-carboxylic acid and/or 3-oxopregna-1,4-diene-20-carboxylic acid from those compounds, even in the absence of inhibitors inhibiting degradation of the steroid ring and/or growth. |
priorityDate | 1981-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.