abstract |
Pirbuterol is prepared by heating 5-hydroxy-2-(1-Ânhydroxy-2-t-butylaminoethyl)pyridine with aqueous formalÂndehyde in the presence of a weak base, e.g. triethylamine. nThe pirbuterol is conveniently isolated as the hydrochloride. nPirbuterol is a well known bronchodilator. |