http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0058047-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 |
| filingDate | 1982-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1984-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0058047-B1 |
| titleOfInvention | Substituted imidazole derivatives and their preparation and use |
| abstract | Compounds of the formula: <IMAGE> (I) <IMAGE> wherein each of R1, R2 and R3, which can be the same or different, is hydrogen, chloro, bromo, fluoro, methyl, ethyl, methoxy, amino, hydroxy or nitro; R4 is hydrogen or alkyl of 1 to 7 carbon atoms; R5 is hydrogen or a straight or branched alkyl group of 1 to 5 carbon atoms or a phenyl group; and R6 is hydrogen or an alkyl group of 1 to 7 carbon atoms or a substituted or unsubstituted benzyl, X is -CH2-, -CHOH- or -CH=CH- and n is 0-4; provided that R5 and R6 are simultaneously hydrogen only when n is 4 and X is -CH=CH-; and their non-toxic pharmaceutically acceptable acid addition salts and mixtures thereof exhibit valuable pharmacological activity and are useful in the treatment of mammals, especially as antithrombotic agents. Furthermore, some of the compounds have proved to possess antihypertensive or beta -blocking activity. Antimicrobial and antifungal properties have also been found. Processes for the preparation of these compounds are described, as are novel pharmaceutical compositions comprising at least one of the compounds or their salts. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104245679-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104245679-A |
| priorityDate | 1981-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 439.