http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0050407-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 |
| filingDate | 1981-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_985dac670a26788b6545ee6e1d087daf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7395fa8a2dd1d7ead589031351be1919 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_588af27c7555bdd7fc0d04ec816dc42c |
| publicationDate | 1982-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0050407-A1 |
| titleOfInvention | 3,5-Disubstituted-1,2,4-triazole compounds, processes for their preparation and pharmaceutical compositions containing them |
| abstract | The invention provides compounds of the general formula (I)n and physiologically acceptable salts, hydrates and bioprecursors thereof in whichn R, represents hydrogen, C 1-10 alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, heteroaralkyl, trifluoroalkyl or C 1-10 alkyl substituted by hydroxy, alkoxy or dialkylamino; or C,., alkyl substituted by cycloalkyl; R, represents hydrogen or a C 1-4 alkyl group; or R, and R 2 may together with the nitrogen atom to which they are attached form a 5-10 membered ring which may be saturated or may contain at least one double bond, may be unsubstituted or substituted by one or more C 1-3 alkyl groups or a hydroxy group and/or may contain another heteroatom, selected from oxygen or sulphur; Alk represents a straight or branched C 1-6 alkylene chain; Q represents a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3-positions or 1- and 4-positions; X represents oxygen, sulphur or a methylene group; n represents zero, 1 or 2; m represents 2, 3 or 4 with the proviso that n + m is at least 3; R 3 represents alkenyl, alkoxy or alkyl substituted by hydroxy, acyloxy, alkoxy, amino, alkylamino, dialkylamino, aryl, heteroaryl or C 1-4 alkylsulphonyl; or R3 represents COR, or CR 4 =NOH where R 4 represents hydrogen or C 1-4 alkyl. n The compounds show pharmacological activity as selective histamine H 2 -antagonists. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022034121-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4748165-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7507729-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4767769-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0181163-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0181163-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4795755-A |
| priorityDate | 1980-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.