http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0047734-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009
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filingDate 1980-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5cb711518d0f96ae68fcf227b9c2b99
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publicationDate 1982-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0047734-A1
titleOfInvention Pharmaceutical vehicle composition and process of producing same
abstract A pharmaceutical vehicle allows direct compression, with an active ingredient, in a tablet manufacturing machine to form a product ready for pharmaceutical administration. The pharmaceutical vehicle or excipient is formed by compacting, in a roller compactor (10), such as a "Chilsonator", of a mixture, in given proportions, of powdered cellulose, preferably alpha cellulose, and double calcium phosphate dihydrate. The compaction of these materials results in a self-supporting sheet which is a compact mixture of the two materials. This sheet is broken, sieved to the appropriate size, and the resulting particles are used to form tablets with active ingredients in a standard tablet press. The tablets obtained are more easily formed and present an improvement, inter alia, as regards friability, disintegration, and dissolution. Small amounts of other materials can be incorporated with powdered cellulose and double calcium phosphate dihydrate.
priorityDate 1980-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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