| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
1981-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8faa4f535bb83b4dbd6d084f2bfb9fc0 |
| publicationDate |
1982-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0044142-A1 |
| titleOfInvention |
Process for the preparation of beta-lactam antibiotics |
| abstract |
The present invention provides a process for the preparation of antibacterially active carbapenems of the formula:n and salts and esters thereof wherein R 1 and R 2 are independently hydrogen or an organic group bonded via a carbon atom and R 3 is a group NR 4 R 5 wherein R 4 optionally substituted alkyl, aryl and aralkyl, and R 5 is hydrogen or optionally substituted alkyl or R 3 is optionally substituted aryl or alkyl: which process comprises the reaction of a C-3 mercapto carbapenem with an aziridine (CH 2 ) 2 NCOR 3 . |
| priorityDate |
1980-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |