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filingDate 1981-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1984-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1984-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0043940-B1
titleOfInvention 3,1-benzoxazin-2-ones, their preparation and their use
abstract The invention relates to compounds of general formula I <IMAGE> (I) (wherein R1 and R2, which may be the same or different, each represents a hydrogen atom or a (C1-C4) alkyl group; R3 and R4, which may be the same or different, each represents a hydrogen, fluorine or chlorine atom or a hydroxy, methyl, ethyl or (C1-C4) alkoxy group, or R3 together with R4 represents a methylenedioxy group; R5 and R6, which may be the same or different, each represents a hydrogen atom or a methyl group; R7 represents a group of formula <IMAGE> R represents a hydrogen atom or a (C1-C4) alkyl group; R8 represents a fluorine or chlorine atom or a (C1-C4) alkyl, (C1-C4) alkylthio, hydroxymethyl, CONHR11, SO2NHR11, OR12, methoxycarbonyl, ethoxycarbonyl or NHSO2CH3 group; R9 represents a hydrogen, fluorine or chlorine atom or a OR12 group; R10 represents a hydrogen or chlorine atom or an amino, methyl or methoxy group; R11 represents a hydrogen atom or a methyl, ethyl or hydroxyethyl group; R12 represents a hydrogen atom or a (C1-C4) alkyl, (C1-C4) alkyl-CO, aryl-CH2 or aryl-CO group; and n represents 1, 2 or 3) and acid addition salts thereof as well as to processes for their preparation and pharmaceutical compositions containing them. The compounds of the invention possess interesting pharmacological properties in particular displaying hypotensive and selective tocolytic effects.
priorityDate 1980-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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