abstract |
Hydroxy, amino and sulfhydryl derivates of 1 or 3-β-D-arabinofuranosyl-1,3 or 4H-imidazo [4,5-c] pyridine, their corresponding esters and non-toxic pharmaceutically acceptable salts are produced by arabinofuranosylation of an anion of requisite heterocycles with 2,3,5-tri-O-benzyl-a-D-arabinofuranosyl halide and further reaction to obtain the desired compounds, which are water-soluble and resistant to adenosine deaminase and exhibit antiviral activity. |