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filingDate 1981-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e642d0512ccc4469482ab77eef17d5c3
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publicationDate 1981-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0042366-A1
titleOfInvention Diphenylbutyl-1-acylpiperazines
abstract PCT No. PCT/SE81/00169 Sec. 371 Date Jan. 25, 1982 Sec. 102(e) Date Jan. 25, 1982 PCT Filed Jun. 5, 1981 PCT Pub. No. WO81/03658 PCT Pub. Date Dec. 24, 1981.Novel compounds of the formula <IMAGE> wherein R' is selected from the group consisting of alkyl straight or branch chained having from 2 to 10 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms, aralkyl having from 7 to 9 carbon atoms, phenyl and substituted phenyl wherein the substituents of the substituted phenyl are selected from the group consisting of one to three F, Cl, Br, lower alkyl having from 1 to 5 carbon atoms, lower alkoxy having from 1 to 5 carbon atoms, alkylenedioxy having from 1 to 3 carbon atoms, -CF3 and -CN and pharmaceutically acceptable salts thereof which have been found to have utility for therapeutic treatment of mental disorders by reducing anti-aggressive behavior and a process for making the compounds.
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