| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D503-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D503-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
1981-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0749f73fbca929d2c40f48172a1926e3 |
| publicationDate |
1981-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0042220-A1 |
| titleOfInvention |
Process for the preparation of beta-lactam antibiotics |
| abstract |
The present invention provides a process for the preparation of a fused bicyclic (β-lactam containing compound having an optionally salified free carboxylic acid group which process comprises the reaction of an ester of the formula (I):n with halide ion; wherein R is the residue of the fused bicyclic (β-lactam containing compound, R' is an alkyl group of 1-6 carbon atoms optionally substituted by an alkoxy group of 1-4 carbon atoms or is an optionally substituted phenyl group or an alkyl group of 1-4 carbon atoms substituted by an optionally substituted phenyl group; and R 2 is a hydrogen atom or an alkyl group of 1-4 carbon atoms or is joined to R 2 to form part of a 5- or 6- membered carbocyclic or heterocyclic ring. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4585638-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4741891-A |
| priorityDate |
1980-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |