| abstract |
New dibenzooxepines usable as medicine and corresponding to the general formula: in which R and R ′, which are identical or different, represent hydrogen, a lower alkyl, a lower alkoxy, a trifluoromethyl, a trifluoromethoxy, a trifluoromethylthio, a halogen, an alkylenedioxy group or an alkylthio radical,n n n A represents an oxygen atom, a sulfur atom, a sulfoxide radical or a sulfonyl radical.n n n R 1 and R 2 , identical or different, represent a hydrogen, a lower alkyl, a lower aralkyl radical, or a lower hydroxyalkyl radical or else together form an alkylene chain having from 3 to 6 carbon atoms which can be interrupted by one or two heteroatoms, optionally substituted by a lower alkyl radical.n n n n represents an integer varying from 2 to 4 m and m ′, which may or may not be identical, represent an integer of 1 or 2.n n n These new compounds and their physiologically tolerable salts can be used in therapy, in particular as psychotropics. |