| abstract |
The invention relates to new 2-alkyl-5-hydroxy-1,4-naphthoquinones of the general formula I <IMAGE> in which Y is methyl, ethyl, n-propyl, isopropyl or tert-butyl group, and a process for Preparation of these compounds and pharmaceutical compositions containing them. The naphthoquinone derivatives according to the invention have excellent prostaglandin synthetase-inhibiting and antiallergic and in particular antianaphylactic properties. They are therefore used to treat and control inflammation and allergic, especially anaphylactic, reactions. |