| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-849 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-675 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-675 |
| filingDate |
1981-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d4563f36680faeac081c3d6d4c1059f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf410672821069a650b98cb15a22619
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44b9c7d78139851028ad0048a706b895 |
| publicationDate |
1981-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0035781-A2 |
| titleOfInvention |
Microbiological syntheses of beta endorphin |
| abstract |
DNA comprising the naturally occurring nucleotide sequence coding for amino acids 44-90 of β-lipotropin and including the entire coding region for β-endorphin with the exception of the C-terminal glutaminewas modified, transferred to an expression transfer vector, and expressed as a fusion protein. The fusion protein was further modified in vitro to yield mature β-endorphin. β-endorphin was purified from a bacterial lysate. The structure and biological activity of the resulting product was proven by immunological assay, and by two independent assays designed to demonstrate biological activity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6596269-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0596459-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0123294-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0596459-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0233044-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0233044-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0112849-B1 |
| priorityDate |
1980-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |