http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0035360-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D225-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 |
| filingDate | 1981-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1983-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0035360-B1 |
| titleOfInvention | 5,6,8,9-tetrahydro-7h-dibenz(d,f)azonine derivatives, the production thereof and compositions containing them |
| abstract | The present invention provides 5.6;8,9-tetrahydro-7H-di- benz(d,f)azonine derivatives of the formula:wherein R<sup>1</sup> and R<sup>2</sup>, which are the same or different, are hydrogen or halogen atoms or lower alkyl or lower alkoxy radicals, R<sup>3</sup> is a hydrogen atom or a lower alkyl radical, R<sup>4</sup> is a hydrogen atom or a lower alkyl or lower alkanoyl radical and n is 1 or 2; and the pharmaceutically acceptable salts thereof formed with inorganic and organic acids; but excluding 6-benzyl-2,12-dimethoxy-1-hydroxy-7-methyl-5,6;8,9-tetrahy- dro-7H-dibenz(d,f)azonine in which case R<sup>1</sup>, R<sup>2</sup> and R<sup>4</sup> are hydrogen, n is 1 and R<sup>3</sup> is methyl. The lower alkyl, lower alkanoyl and lower alkoxy radicals are straight chain or branched radicals containing 1 to 5 carbon atoms.The present invention also provides a process for the production of these compounds, as well as pharmaceutical compositions containing them.The compounds are useful as antiarrhythmic agents and as local anaesthetics; they do not cause some of the unsatisfactory side effects associated with known agents. |
| priorityDate | 1980-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.