| abstract |
A process for the preparation of a polypeptide containing the amino acid sequence of human interferon, in which the genetic information for the biosynthesis of the named polypeptide is obtained by means of fibroblast m-RNA, from which the cDNA is prepared, which is inserted into a plasmid, with the obtained Hybrid plasmid transforms microorganisms and, by selection and cultivation, the microorganisms producing the polypeptide are obtained. |