| abstract |
Novel intermediates for non-ionic polyiodo amino- substituted benzenepolyamides having polyol substituents on the amide nitrogens are provided which are 5-amino-6-hydroxy-1,3-dioxepanes. The compounds provide an economic and efficient route to novel contrast media having excellent chemical and physiological properties. n Also provided are methods for preparing the subject compounds. n The invention described herein was made in the course of work under a grant from the United States Department of Health, Education and Welfare. |