http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0033255-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1981-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78f67a56c7ad3e0d030688e65ebc4d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca91d9e6b567eb91c97d264a977d4c0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_859e7c627ac18d7aab76b9a4b4d38c07 |
| publicationDate | 1981-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0033255-A1 |
| titleOfInvention | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them |
| abstract | - les dérivés 1 et leurs sels avec les acidesn A est un alkylène (1 à 6 carbones), R est alkyloxy, alkényloxy, alkynyloxy, alkylthio, alkénylthio, alkynylthio (au plus 6 carbones), le soufre étant éventuellement oxydé, aryloxy, aralkyloxy, arylthio, aralkylthio, le soufre étant éventuellement oxydé, NR 1 R 2 , où R 1 et R 2 son hydrogène, alkyle (1 à 6 carbones) ou forment un hétérocycle, ou R est un ammonium quaternaire, un halogène, un radical 1,2,-époxyéthyle éventuellement substitué et éventuellement ouvert par un nucléophile, 0-CO-B où B est alkyle, alkyloxy (1 à 6 carbones), aryle, aralkyle, aryloxy, aralkyloxy, ou R est un formyle libre ou protégé, un carbonyle libre, estérifié ou salifié, un thiocya- nate, nitrile, acyle, carbamoyle, et R est hydrogène ou acyle, leur préparation à partir de l'érythromycine ou de sa 9-oxime, leur application comme médicaments antibiotiques et les compositions les renfermant. The invention relates to derivatives 1 and their salts with acids A is an alkylene (1 to 6 carbons), R is alkyloxy, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio (at most 6 carbons), the sulfur being optionally oxidized, aryloxy, aralkyloxy, arylthio, aralkylthio, the sulfur being optionally oxidized, NR 1 R 2 , where R 1 and R 2 are hydrogen, alkyl (1 to 6 carbons) or form a heterocycle, or R is a quaternary ammonium, a halogen, a 1,2, -epoxyethyl radical optionally substituted and optionally opened with a nucleophile, O-CO-B where B is alkyl, alkyloxy (1 to 6 carbons), aryl, aralkyl, aryloxy, aralkyloxy, or R is a free or protected formyl, a free carbonyl, esterified or salified, a thiocyanate , nitrile, acyl, carbamoyl, and R is hydrogen or acyl, their preparation from erythromycin or its 9-oxime, their use as antibiotic drugs and the compositions containing them. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0158467-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014077712-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017174593-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2534588-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/LT-4276-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0158467-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1046535-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9618633-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AP-739-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0422843-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0422843-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MD-1788-G2 |
| priorityDate | 1980-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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