http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0032387-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-69 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-69 |
| filingDate | 1981-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f23af99c7eb8de35c94a41cf1ea8d244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbaa4cc1922bfffe869a57e2447d32ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba23c9c14ff6c0e51d92af5cbf593907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266e3cdf59e253c2cb2eaa2001c8bf51 |
| publicationDate | 1981-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0032387-A1 |
| titleOfInvention | Non ionic 5-C-substituted 2,4,6-triiodo-isophthalic acid derivatives, process for their preparation and X-ray contrast agents containing them |
| abstract | X den Rest-CO-N-R 1 R 2 ,-COOR 3 ,-CH 2 ·NH·R 7 oder-CH 2 OH. Y den Rest-N-R 1 R 2 oder-OR, Z den Rest -N·R 1 R 2 , -NH·R 7 , -NH·Zuckerrest oder -OR 3 , wobei -NR 1 R 2 in X, Y und Z gleich oder verschieden sind, R 1 und R 2 gleich oder verschieden sind und ein Wasserstoffatom oder einen gegebenenfalls mono-oder polyhydroxylierten gerad- oder verzweigtkettigen Alkylrest, R 3 einen niederen, gegebenenfalls hydroxylierten Alkylrest und R, den Acylrest einer gegebenenfalls hydroxylierten niederen aliphatischen Carbonsäure, wobei anwesende OH-Gruppen auch funktionell abgewandelt sein können, bedeuten. The invention relates to new, nonionic, in the 5-position C-substituted 2,4,6-triiodoisophthalic acid derivatives of the general formula wherein X is the residue -CO-NR 1 R 2 , -COOR 3 , -CH 2 · NH · R 7 or -CH 2 OH. Y is the residue NR 1 R 2 or OR, Z represents the radical —N · R 1 R 2 , —NH · R 7 , -NH · sugar residue or -OR 3 , where -NR 1 R 2 in X, Y and Z are identical or different, R 1 and R 2 are the same or different and represent a hydrogen atom or an optionally mono- or polyhydroxylated straight or branched chain alkyl radical, R 3 is a lower, optionally hydroxylated alkyl radical and R, the acyl radical of an optionally hydroxylated lower aliphatic carboxylic acid, where OH groups present can also be functionally modified. n n n Because of their good pharmacological and physicochemical properties, the new compounds of the formula I are outstandingly suitable as shading substances in all areas of application of water-soluble iodine-containing X-ray contrast media. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7166740-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0614668-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0406992-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0614668-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7355067-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005005363-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0406992-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005005362-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0073715-A1 |
| priorityDate | 1980-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.