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filingDate 1980-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1981-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0029117-A1
titleOfInvention 10-Bromosandwicine and 10-bromoisosandwicine, as well as their additions salts with pharmacolical acceptable acids process for their preparation and their use
abstract 10-Bromosandwicin can be obtained by brominating Sandwicin with a suitable brominating agent. Suitable brominating agents are bromine, copper (II) bromide or 2,4,4,6-tetrabromo-2,5-cyclohexadien-1-one. It is convenient to work in an inert solvent.n n n 10-bromoisosandwicin is accessible by isomerization of 10-bromosandwicin under alkaline conditions.n n n 10-bromosandwicin and 10-bromoisosandwicin are valuable substances for the production of pharmacologically active compounds.
priorityDate 1979-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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