http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0028083-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D503-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D503-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1980-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc0f280fdf7aabcc6d7440cf0a9d1ef6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c3261a91315b2a9ca68d7658d7c44a5 |
| publicationDate | 1981-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0028083-A1 |
| titleOfInvention | Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them |
| abstract | This invention provides the compounds of the formula (II)n and pharmaceutically acceptable salts and esters thereof, wherein A is an oxygen or sulphur atom or is a group NR 5 , wherein R 5 is a hydrogen atom or a C 1-6 alkyl C 1-6 alkanoyl, C 1-6 alkoxycarbonyl, arylcarbonyl or aralkylcarbonyl group, any of such groups being optionally substituted by C 1-3 alkyl, C 1-3 alkoxy, hydroxy, C 1-3 alkanoyloxy, or esterified or salified carboxy: or R 5 is a group of the sub-formula (i):n wherein X is a bond or a -CH 2 - moiety; R 6 is hydrogen, fluorine, chlorine, bromine, C 1-3 alkyl, C 1-3 alkoxy or hydroxy; R 7 is hydrogen or C 1-3 alkyl, and R 8 is hydrogen or C 1-3 alkyl; and R 3 and R 4 are independently hydrogen or C 1-6 alkyl; these compounds are useful as antibacterial agents and as β-lactamase inhibitors. Their preparation and use are described. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9120808-B2 |
| priorityDate | 1979-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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