| abstract |
The invention is to provide a new process for producing daunomycin and baumycins having potent antitumor activity and low toxicity by microbial conversion of anthracyclinones such as aklavinone and ε-rhodomycinone, using microorganism selected from the group consisting of Streptomyces coeruleorubidus ME130-A4 (FERM-P 3540), Streptomyces peucetius subsp. carneus ATCC 21354, Streptomyces coeruleorubidus ATCC 13740, Streptomyces peucetius NRRL B-3826 (FERM-P 3989) and their mutants. |