| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aac141a3051e128a54ab3843e7aa47e2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02 |
| filingDate |
1980-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9229338a2bd9a072f7f25c9a6ecc607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_144f699e058386532babec39337fa045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59fb819156b4498aa56f4a2d38296170
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a5c6758ad8655280ed6fe6c6f038af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6886813cb70a87e854ca5151b83268d |
| publicationDate |
1981-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0024547-A2 |
| titleOfInvention |
Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding alpha-hydroxy carbonic acids |
| abstract |
Water-soluble α-ketocarboxylic acids are continuously converted into the corresponding a-hydroxycarboxylic acids in a membrane reactor. The conversion takes place in the presence of a substrate-specific dehydrogenase and of nicotinamide adenine dinucleotide (NAD * / NADH) as coenzyme by binding to a water-soluble polymer with an average molecular weight between 500 and 50,000. At the same time, NAD + is continuously regenerated from NADH in the presence of a formate dehydrogenase and formations. The membrane must have an average pore diameter of 1 to 3 nm. The coenzyme is used in a concentration of 0.1 to 10 mmol / 1. A substrate stream which contains 50 to 100% of the maximum soluble amount but not more than 2,000 mmol / l of the a-ketocarboxylic acid to be reacted in the form of a water-soluble salt and 100 to 6,000 mmol of a formate is fed continuously to the reactor. A differential pressure of 0.1 to 15 bar is maintained across the membrane. A filtrate stream containing the a-hydroxycarboxylic acid formed is continuously removed behind the membrane. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0218863-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5256552-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0347374-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0144832-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0130288-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0357787-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0357787-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0130288-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0144832-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0218863-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0394448-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0394448-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0304781-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0304781-A2 |
| priorityDate |
1979-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |