| abstract |
The invention relates to indole derivatives: <IMAGE> as well as their salts with acids, formula I where X is alkyl of 1 to 6 carbons, cycloalkyl of 5 or 6 carbons, cycloalkyl-alkyl of 4 to 7 carbons, alkenyl of 2 to 5 carbons, alkynyl of 3 to 5 carbons, aralkyl of 7 to 12 carbons, hydroxyalkyl of 2 to 5 carbons, a phenoxyalkyl with alkyl of 1 to 5 carbons, R is hydrogen, halogen, alkoxy of 1 to 3 carbons , nitro, amino, trifluoromethyl or methylthio, R1 and R2 are hydrogen or alkyl of 1 to 3 carbons, it being understood that if R is hydrogen, halogen or alkoxy, X is hydroxyalkyl or phenoxyalkyl. The invention also relates to a process for obtaining the products I, their application as medicaments, in particular neuroleptics, antipsychotics and antiemetics, as well as the compositions containing them. |