Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03721e344a72026d125291e6c56c1be6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 |
filingDate |
1980-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f47d9f81368c74f2cc0b966dd135ebe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b412fdc4e8dabc1a1c868ce586a46c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db8c2b6d3898725bbf7043b5f5f5c39e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcc2cb832cdc1190c6390a114a951c7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f02c25db874275ae5c5648275b7c1b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8192a98b70e158b7c7ce73af05598c78 |
publicationDate |
1980-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0016157-A1 |
titleOfInvention |
7-0-(2,6-dideoxy-alpha-l-lyxo-hexopyranosyl)-desmethoxy-adriamycinone |
abstract |
The compounds have a great antileukemic activity on murine P 388 leukemia and a better aqueous solubility due to the substitution of the NH2 group by an OH group in position 3 'of exopyranose, ie daunosamine. These compounds are binding products of the desmethoxy daunomycinone aglycone, ordriamycinone and carminomycinone. These compounds are linked in position 0-7 of the aglycone with an (Alpha) -L-lyxo hexopyranose, the isomer of this carbohydrate supporting in particular or reinforcing the biological activity of the binding compound while decreasing the cardiotoxicity of the compounds known. These compounds correspond to formula: |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8840429-B2 |
priorityDate |
1978-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |